The Kangchenjunga landscape is a complex of three distinct ecoregions: the eastern Himalayan broad-leaved and coniferous forests, the Eastern Himalayan alpine shrub and meadows and the Terai-Duar savanna and grasslands. The Kangchenjunga transboundary landscape is shared by Nepal, India, Bhutan and China, and comprises 14 protected areas with a total of 6,032 km2.

• Nepal: Kanchenjunga Conservation Area
• Sikkim, India: Khangchendzonga National Park, Varsey Rhododendron Sanctuary, Fambong Lho Wildlife Sanctuary, Kyongnosla Alpine Sanctuary, Maenam Wildlife Sanctuary, Shingba Rhododendron Sanctuary and Pangolakha Wildlife Sanctuary
• Darjeeling, India: Jore Pokhri Wildlife Sanctuary, Singalila National Park, Senchal Wildlife Sanctuary, Mahananda Wildlife Sanctuary and Neora Valley National Park
• Bhutan: Torsa Strict Nature Reserve

These protected areas are habitats for many globally significant plant species such as rhododendrons and orchids and many endangered flagship species such as snow leopard (Panthera uncia), Asian black bear (Ursus thibetanus), red panda (Ailurus fulgens), white-bellied musk deer (Moschus leucogaster), blood pheasant (Ithaginis cruentus) and chestnut-breasted partridge (Arborophila mandellii).